Test Specification Min Max ASSAY 97 102.00% EXPIRATION DATE

Test Specification Min Max ABSORPTION MAX 630 (422) nm 630 (422) nm

Test Specification Min Max SPECIFIC ROTATION, [(a)]D[@20@] (C = 10; H[@2@]O; DRIED BASIS) +197� to +201� +197� to +201� WATER (BY KF) 8.5 11.00% RESIDUE ON IGNITION 0.05% HEAVY METALS...

Test Specification Min Max ASSAY (DRIED BASIS) 99%

Test Specification Min Max APPEARANCE

Test Specification Min Max CARBON NUMBER AT 5% DISTILLATION POINT 28 SPECIFIC GRAVITY 0.845- 0.905 0.845- 0.905 UV ABSORBANCE (POLYNUCLEAR HYDROCARBONS) TO PASS TEST TO PASS TEST VISCOSITY @ 100[d...

Test Specification Min Max CARBON NUMBER AT 5% DISTILLATION POINT 17 25 SPECIFIC GRAVITY @ 25�C 0.829 0.859 ULTRAVIOLET ABSORBANCE (POLYNUCLEAR HYDROCABONS) TO PASS TEST TO PASS TEST VISCOSITY @...

Test Specification Min Max ASSAY (C[@8@]H[@8@]O[@3@]; DRIED BASIS) 99 100.50% MELTING RANGE 125� 128�C ACIDITY TO PASS TEST LEAD (Pb) 2 mg/kg LOSS ON DRYING 0.50% RESIDUE ON IGNITION 0.05%...

Test Specification Min Max APPEARANCE FINE,WHITE,CRYST FINE,WHITE,CRYST ASSAY (C[@6@]H[@14@]O[@6@]; DRIED BASIS) 96.0 - 101.5 % 96.0 - 101.5 % APPEARANCE OF SOLUTION (2 g in 20 ml) CLEAR AND COLORL...

Test Specification Min Max VISUAL TRANSITION INTERVALS pH 4.5 (red) to pH 4.5 (red) to

Test Specification Min Max APPEARANCE

Test Specification Min Max APPEARANCE

Test Specification Min Max ASSAY 99% APPEARANCE CLEAR LIQUID CLEAR LIQUID

Test Specification Min Max APPEARANCE APPEARANCE

Test Specification Min Max ASSAY Approx. 2.5 % Approx. 2.5 %

Test Specification Min Max APPEARANCE EXPIRATION DATE

Test Specification Min Max APPEARANCE

Test Specification Min Max ASSAY 98.50%

Test Specification Min Max ASSAY (C[@13@]H[@6@]Cl[@6@]O[@2@]) 98.0 - 100.5 % 98.0 - 100.5 % MELTING POINT 161 - 167 C 161 - 167 C LOSS ON DRYING 1.00% RESIDUE ON...

Test Specification Min Max ASSAY (DRIED BASIS) 98.5 101.00% MELTING RANGE 130.5 - 134.5�C 130.5 - 134.5�C LOSS ON DRYING 0.50% ORGANIC IMPURITIES TO PASS TEST TO PASS TEST RESIDUE...

Test Specification Min Max APPEARANCE EXPIRATION DATE MANUFACTURE DATE

Test Specification Min Max NO SPECIFICATIONS

Test Specification Min Max ASSAY (ANHYDROUS BASIS) 99 101.00% COLOR AND CLARITY OF SOLUTION TO PASS TEST TO PASS TEST FUMARIC ACID 1.50% IRON (Fe) 5 ppm ELEMENTAL IMPURITIES AS...

Test Specification Min Max ASSAY (as MINOCYCLINE, ANHYDROUS BASIS) 890 - 950 �g/mg 890 - 950 �g/mg pH (10 mg of MINOCYCLINE per mL) 3.5 4.5 WATER 9% 9% IDENTIFICATION...

Test Specification Min Max CHLORIDES 0.01% SULFATE 0.01% BARIUM 0.30% MAGNESIUM AND ALKALIES (as SO[@4@]) 0.30% NITRATE (NO[@3@]) 0.01% WATER INSOLUBLE MATTER 0.05% HEAVY METALS (as Pb) 0.00% IRON 0.00%...

Test Specification Min Max ASSAY (C[@6@]H[@6@]N[@2@]O) 98 101.00% MELTING RANGE 128� 131�C HEAVY METALS (as Pb) 0.00% LOSS ON DRYING 0.50% READILY CARBONIZABLE SUBSTANCES TO PASS TEST RESIDUE ON IGNITION...

Test Specification Min Max PURITY (Nonaqueous Titration) 98.00%

Test Specification Min Max APPEARANCE

Test Specification Min Max ASSAY 94.50%

Test Specification Min Max APPEARANCE

Test Specification Min Max ABSORPTION MAX 476 (418) nm 476 (418) nm

Test Specification Min Max COMPLETENESS AND COLOR OF SOLUTION TO PASS TEST TO PASS TEST pH OF A 5% SOLUTION @ 25[dC 4.5 - 7.5 4.5 - 7.5 RESIDUE ON...

Test Specification Min Max APPEARANCE

Test Specification Min Max ASSAY 98% 98%

Test Specification Min Max ASSAY APPROX. 90 % APPROX. 90 %